ADCIRCA® (tadalafil)
We’re behind you all the way.
We’re here to help you start ADCIRCA and provide support along the way. Whether you have questions about insurance, cost, or taking your medication, our full team of specialists is here to point you to answers.
Get treatment support
Your team is here for you.
Our team is a resource to guide you through getting, starting, and continuing your medication. If you have questions about taking your medication, our Patient Education Specialists can help.

Your United Therapeutics Cares team
We’ll be there from the start to help set expectations for what’s ahead. We can also connect you to other specialists with the knowledge and understanding you need.

Our Specialty Pharmacy network
Once your prescription is ready, you’ll be set up with a Specialty Pharmacy, which will be your source for information about prescription deliveries and refills.

Community organizations
Sometimes it helps to talk with others who truly understand. We can point you to organizations that offer support, resources, and community.
Find financial support
Explore all your options.
Cost is a common worry when it comes to treatment. Depending on your situation, there may be options that can help lower what you pay for your prescription. An Access & Affordability Specialist can walk you through what may be available.
Co-pay assistance
If you have a commercial insurance plan, our co-pay assistance program can help cover your out-of-pocket costs. Visit our co-pay site to learn if you are eligible to pay as little as a $0 co-pay per prescription. The United Therapeutics Cares Co-Pay Assistance Program will automatically pay the difference up to the monthly maximum program benefit.*
Visit co-pay site *Patients must meet certain eligibility criteria to qualify for assistance.Co-pay assistance
If you have a commercial insurance plan, our co-pay assistance program can help cover your out-of-pocket costs. Visit our co-pay site to learn if you are eligible to pay as little as a $0 co-pay per prescription. The United Therapeutics Cares Co-Pay Assistance Program will automatically pay the difference up to the monthly maximum program benefit.*
Visit co-pay site *Patients must meet certain eligibility criteria to qualify for assistance.Patient Assistance Program
If you don’t have insurance, or if your coverage doesn’t go far enough, you may qualify for our Patient Assistance Program. Reach out to our team to learn more about eligibility.
Reach outPatient Assistance Program
If you don’t have insurance, or if your coverage doesn’t go far enough, you may qualify for our Patient Assistance Program. Reach out to our team to learn more about eligibility.
Reach outAdditional financial resources
We want to help you find every option that’s available to you. If you need more support than what our program offers, explore additional financial resources through RE Assist, an online tool for finding healthcare financial support.
Visit RE AssistAdditional financial resources
We want to help you find every option that’s available to you. If you need more support than what our program offers, explore additional financial resources through RE Assist, an online tool for finding healthcare financial support.
Visit RE AssistLearn how we help
See the full picture.
Knowing what’s ahead can help make everything easier. Learn how United Therapeutics Cares works, from enrollment and onboarding to ongoing support.

Support starts with enrollment.
To enroll in United Therapeutics Cares, you’ll need to sign the consent and authorization form.
Enroll nowPlease see below for Important Safety Information
- You should discuss all of your medical conditions and all medications with your healthcare provider before starting ADCIRCA
- Do not take ADCIRCA if you take any medications that contain nitrates (often used for chest pain) or guanylate cyclase stimulators, as the combination could cause a sudden, unsafe drop in blood pressure
- Do not take ADCIRCA if you are allergic to tadalafil or any other ingredient in ADCIRCA
- ADCIRCA is a type of medication called a phosphodiesterase 5 inhibitor (PDE-5i) that can cause blood vessels to widen, which may result in a decrease in blood pressure. If you have heart-disease or any problems with low blood pressure, tell your healthcare provider before taking ADCIRCA, as these conditions may be affected by the action of ADCIRCA
Important Safety Considerations for ADCIRCA® (tadalafil)
- You should discuss all of your medical conditions and all medications with your healthcare provider before starting ADCIRCA
- Do not take ADCIRCA if you take any medications that contain nitrates (often used for chest pain) or guanylate cyclase stimulators, as the combination could cause a sudden, unsafe drop in blood pressure
- Do not take ADCIRCA if you are allergic to tadalafil or any other ingredient in ADCIRCA
- ADCIRCA is a type of medication called a phosphodiesterase 5 inhibitor (PDE-5i) that can cause blood vessels to widen, which may result in a decrease in blood pressure. If you have heart-disease or any problems with low blood pressure, tell your healthcare provider before taking ADCIRCA, as these conditions may be affected by the action of ADCIRCA
- Talk with your healthcare provider if you are pregnant or planning to become pregnant or if you are breastfeeding or plan to breast feed.
- If you have ever had blockage in the veins of your lungs, known as pulmonary veno-occlusive disease (PVOD), ADCIRCA is not recommended for you
- Taking ADCIRCA with alcohol, or blood pressure medications, such as alpha-blockers, may lower blood pressure and cause hypotension (light-headedness or fainting)
- Do not take ADCIRCA if you are taking rifampin (an antibiotic for certain bacterial infections), or antifungal medications, such as ketoconazole and itraconazole. If you require treatment with both ADCIRCA and ritonavir (Norvir®) at the same time, your dose of ADCIRCA will need to be adjusted. Inform your healthcare provider if you have kidney or liver problems before taking ADCIRCA
- ADCIRCA contains the same ingredient (tadalafil) as Cialis®, which is used to treat erectile dysfunction (ED, impotence) and the signs and symptoms of benign prostatic hyperplasia (BPH, enlarged prostate). If you are taking ADCIRCA, do not take Cialis or other PDE-5is
- In rare cases, patients reported side effects such as decreased eyesight or loss of vision in one or both eyes (NAION), or sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness. If you experience any of these side effects after taking ADCIRCA, seek medical attention right away
- In rare cases, men taking PDE-5is (including tadalafil) for erectile dysfunction reported side effects such as an erection lasting more than four hours. If you experience a prolonged erection, seek medical attention right away
- The most common side effects of ADCIRCA are headache, muscle pain, getting red or hot in the face (flushing), nausea, pain in the arms, legs or back, upset stomach, stuffy or congested nose
ADC.ISI.CON.SEP2020
For more information about ADCIRCA, please see the
Full Prescribing Information
and
Patient Information
or call 1-800-545-5979.
Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.

